RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
mir-30a
RNA ID
RNA Type
miRNA
Alteration Pattern
hydroxymethylation
Species
mus musculus
Detection Methods
qRT-PCR; Dual-luciferase reporter assay; Masson's trichrome staining etc.
Target
Tet1
Pathway
NA
PubMed ID
Title
MiR-30a as Potential Therapeutics by Targeting TET1 through Regulation of Drp-1 Promoter Hydroxymethylation in Idiopathic Pulmonary Fibrosis
Year
2017
Function
MiR-30a could inhibit TET1 expression through base pairing with complementary sites in the 3'untranslated region to inhibit Drp-1 promoter hydroxymethylation and therefore inhibiting pulmonary fibrosis.